Officially, the term is reserve/injured list, but it's commonly referred to as injured reserve or IR. Players are put on IR when they have a football-related injury that requires them to miss at least a few weeks. Players on IR don't count against the 53-man active roster limit, but their salaries count against the salary cap.
Players on IR must miss a minimum of four games. Teams may designate up to eight players to return from IR during the regular season (and up to 10 if a team makes the postseason). An individual player can be designated twice.
Once a player on IR is cleared to practice, they have 21 days to either be activated to the active roster or be placed on season-ending IR. They can also be released or traded.
Players who are placed on IR before the start of the regular season can miss the entire season, unless they are designated to return when the roster is trimmed to 53 players prior to the start of the season.
Before Larison's IR designation, Patriots insider Phil Perry released his 53-man roster projection early Sunday and it included Larison.
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